Job Description

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and  comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic. You’ll thrive in an environment that supports innovation, is committed to ending racism and supporting diversity, equity and inclusion, and provides the resources you need to succeed.

Benefits Highlights

• Medical: Multiple plan options.
• Dental: Delta Dental or reimbursement account for flexible coverage.
• Vision: Affordable plan with national network.
• Pre-Tax Savings: HSA and FSAs for eligible expenses.
• Retirement: Competitive retirement package to secure your future.

Responsibilities

Independently sets up and performs experiments and procedures in support of lab goals and grant commitments (e.g. assays, cell/tissue culture, animal studies, etc.). Contributes to the planning, design and modification of studies and experiments in the research lab setting. Monitors results, reports unusual outcomes and suggests modifications. Collects, enters, summarizes, and analyzes data. May oversee and assist with the training of residents, fellows and temporary lab personnel in lab techniques. Works with minimal supervision and performs assignments independently as discussed and approved by Principal Investigator.

Additional Information : 

Lab Overview:
The Lab of Dr. Andrew Haak at Mayo Clinic is seeking a highly motivated and experienced Senior Research Technologist to join our dynamic team. Our lab brings together diverse skill sets in medicinal chemistry, molecular pharmacology and cellular physiology and uses creative approaches to high-throughput screening, synthetic chemistry and drug repurposing to develop novel molecular tools and therapies for rare and ultra rare diseases. 

Position Overview:
The Senior Research Technologist will play a key role in establishing, managing, and advancing the organic chemistry capabilities of our lab. The successful candidate will assist the PI in selecting appropriate equipment to support our expansion, designing and synthesizing novel compounds, performing rigorous analytical validation, and maintaining accurate cataloging systems for synthesized compounds. 

Key Responsibilities:

• Program Development: Lead the establishment and growth of the organic chemistry program within the lab, working closely with the PI to define the scope, goals, and timelines of research projects.
• Equipment Selection: Assist the PI in selecting and procuring laboratory equipment for organic synthesis and related processes. Ensure all equipment is properly maintained and optimized for the lab’s needs.
• Compound Design & Synthesis: Design, synthesize, and purify novel organic compounds for research purposes, using a variety of synthetic organic chemistry techniques. Troubleshoot synthesis challenges and optimize reaction conditions.
• Analytical Validation: Perform analytical validation of synthesized compounds using techniques such as NMR, HPLC, LC-MS, and other relevant methods. Interpret data and ensure the quality and purity of compounds.
• Cataloging & Documentation: Maintain detailed records of synthesis protocols, analytical data, and compound inventories. Implement an efficient system for cataloging compounds and ensuring data integrity and accessibility.
• Project Management: Manage organic synthesis projects from inception to completion, including coordinating resources, ensuring project timelines are met, and troubleshooting issues as they arise.
• Collaboration & Mentoring: Work closely with other members of our diverse research team, including chemists, biologists, and physicians to integrate organic chemistry into broader research objectives. Mentor junior lab staff and provide training in synthetic techniques and analytical methods.

Qualifications

Requires bachelor's degree in biology, chemistry, or other relevant science with 4 years of research laboratory experience. Master's degree in biology, chemistry, or other relevant science preferred.

Additional Preferred Qualifications: 

Qualifications:

• Ph.D. or M.S. in Organic Chemistry/Medicinal Chemistry or a related field with significant experience in synthetic chemistry and laboratory management is preferred.
• Extensive experience with a variety of organic synthesis techniques (e.g., cross-coupling reactions, functional group interconversions, protecting group chemistry) and purification methods (e.g., column chromatography, recrystallization).
• Proficiency with analytical techniques, including NMR, MS, HPLC, and other relevant instruments.
• Experience with lab equipment selection, installation, and troubleshooting.
• Strong organizational skills and attention to detail, with experience in managing lab resources and inventory.
• Excellent communication and collaboration skills, with a demonstrated ability to work effectively as part of a multidisciplinary team.
• Proven ability to manage and prioritize multiple projects and meet deadlines.

Additional Preferred Skills :

• Experience in designing compounds for specific biological or chemical targets.
• Familiarity with software for chemical structure drawing and data analysis (e.g., ChemDraw, Marvin Sketch).
• Experience with compound screening or high-throughput methods is a plus.

Exemption Status

Exempt

Compensation Detail

$64,500.80 - $96,824.00 / year Education, experience and tenure may be considered along with internal equity when job offers are extended.

Benefits Eligible

Yes

Schedule

Full Time

Hours/Pay Period

80

Schedule Details

Monday - Friday (During Standard Business Hours)

Weekend Schedule

Occasional weekends maybe necessary to meet the needs of research.

International Assignment

No

Site Description

Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives.  Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.

Affirmative Action and Equal Opportunity Employer

As an Affirmative Action and Equal Opportunity Employer Mayo Clinic is committed to creating an inclusive environment that values the diversity of its employees and does not discriminate against any employee or candidate. Women, minorities, veterans, people from the LGBTQ communities and people with disabilities are strongly encouraged to apply to join our teams. Reasonable accommodations to access job openings or to apply for a job are available.

Recruiter

Matt Burdick

Job Tags

Full time, Temporary work, Flexible hours, Monday to Friday,

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