Job Description

Job Description

Position Overview

This is a regular, full-time, on-site position based at our New Haven, Connecticut facility.

We are seeking a highly motivated and experienced Senior Clinical Research Nurse (CRN) to join our dynamic clinical research team. The Senior CRN plays a pivotal role in the conduct of clinical research studies, serving as both a study lead and a key resource for protocol execution and participant care. This role ensures the safety, well-being, and rights of research participants while maintaining compliance with study protocols, Good Clinical Practice (GCP), and all applicable regulatory requirements.

As a senior member of the clinical team, this position will be responsible for managing complex trials, overseeing investigational product administration and accountability, coordinating clinical procedures, conducting assessments, and ensuring accurate and timely documentation of study data. The Senior CRN will collaborate closely with investigators, research coordinators, research nurses, imaging staff, and multidisciplinary teams to support study start-up, execution, and close-out activities.

This position offers the opportunity for meaningful participant interaction and impactful contributions to advancing research in neurodegenerative diseases. The ideal candidate is proactive, detail-oriented, and thrives in a fast-paced, collaborative environment. Prior clinical research experience is required, along with experience in team management and/or serving in a lead role.

Key Responsibilities:

• Demonstrates advanced competency in a broad range of clinical nursing skills within the Registered Nurse’s scope of practice, as defined by the Connecticut Department of Health. This includes, but not limited to: vital sign monitoring, phlebotomy, arterial line maintenance, IV insertion and maintenance, electrocardiogram (ECG) acquisition, cognitive rating scale administration, investigational medicinal product management and assistance with sterile invasive procedures under physician supervision.

• Serves as a primary point of contact for study participants throughout their involvement complex, Phase I-IV clinical trials, conducting the informed consent process, providing post-procedure education, and addressing questions or concerns.

• Act as primary point of contact for sponsors, monitors, vendors, and investigators for assigned studies.

• Provide mentorship and training to Clinical Research Nurses, Clinical Research Coordinators, and study support staff to reinforce their professional development and ensuring adherence to Good Clinical Practices (GCP) and protocol procedures.

• Independently manages the day-to-day operations of multiple, active, complex clinical trials simultaneously, including participant recruitment, screening, enrollment, scheduling and visit execution in alignment with Good Clinical Practice (GCP) guidelines, study protocols, and regulatory requirements.

• Maintains subject matter expert level of knowledge of and strict adherence to all assigned study protocols, standard operating procedures (SOPs), and working instruction documents (WIDs) as outlined in the job-specific training matrix.

• Manage and monitor regulatory compliance, including protocol deviations and safety event reporting, and work with regulatory personnel on documentation and submissions.

• Oversee the study team’s workload and ensure effective delegation of tasks to optimize productivity and operational efficiency.

• Oversee the scheduling of participant visits for assigned studies, including coordination of travel logistics, stipend processing, and site calendar review to ensure a seamless and positive participant experience.

• Other duties as assigned by the direct supervisor.

Qualifications and Requirements: 

•  Active Registered Nurse (RN) license in the State of Connecticut, in good standing (required).

•  Bachelor of Science in Nursing (BSN) degree preferred; Associate of Science in Nursing (ADN) degree accepted.

•  Minimum 5+ years of clinical research nursing experience .

• Active Basic Life Support (BLS) certification

• Advanced understanding of Good Clinical Practice (GCP), Good Documentation Practices (GDP), human subjects’ protection, and applicable institutional, local, state, and federal regulations related to clinical research.

• Ability to effectively communicate complex clinical and regulatory concepts in clear, accessible language for participants and non-clinical audiences.

• Skilled in building rapport with diverse participant populations and cross-functional team members, fostering trust and collaboration.

• Strong critical thinking, problem-solving, and professional judgment in clinical and research-related decision-making.

• Proficient in standard Microsoft computer programs (i.e. Outlook, SharePoint, MS Word, Excel, PowerPoint etc)

Preferred but not required:

• Demonstrated managerial experience with direct reports, including performance management, mentorship, and team development.

• Experience working with patients affected by neurological disorders, such as Parkinson’s Disease, Alzheimer’s Disease, Multiple Sclerosis, and similar tauopathies.

• Familiarity with nuclear medicine imaging techniques (PET-CT, SPECT-CT, MRI)

• Advanced Cardiovascular Life Support (ACLS) certification

• CCRC Certification, ACRP-CP Certification, and/or CCRP Certification.

• Multilingual candidates are encouraged to apply, particularly those fluent in both English and Spanish.

• Proficiency in data management tools, clinical trial management systems and electronic data capture

Unique Department Requirements:

• Exposure to ionizing radiation

• Biohazard exposure to human blood and bodily fluids

• Ability to lift and move up to 50 lbs (for heavy equipment and patient positioning)

• Intermittent evening and weekend work may be required

• Travel to meetings may be required

What We Offer:

· Competitive Salary

· Comprehensive Health Insurance Plan

· Long-Term Disability

· Life Insurance

· Retirement Plan

XingImaging, a Mitro Company provides equal employment opportunities to all employees and applicants for employment without regard to race, color, creed, ancestry, national origin, citizenship, sex or gender (including pregnancy, childbirth, and pregnancy-related conditions), gender identity or expression (including transgender status), sexual orientation, marital status, religion, age, disability, genetic information, service in the military, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Equal employment opportunity applies to all terms and conditions of employment, including hiring, placement, promotion, termination, layoff, recall, transfer, leave of absence, compensation, and training.

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