If you are experiencing a problem such as erectile dysfunction, it is likely that in addition to visiting a specialist doctor, or even instead, you are trying to find as much information on the Internet as possible about your condition and how you can get rid of it. There is a wealth of information on the web about drugs used in the treatment of erectile dysfunction (ED), and it is easy to get acquainted with the features of the most popular drugs such as Viagra, Cialis and Levitra. However, it is likely that you have come across completely different names of drugs for ED, and with a large number of them. This is explained very simply: most of these drugs are generics of the already mentioned "big three". By the way, they all belong to the group of PDE-5 inhibitors.
Viagra generics are the most widespread on the modern pharmaceutical market. Among them there are a variety of versions: absolute analogues of the original medicine, as well as modified ones, for example, with a modified form of release (soft tablets or sachets instead of traditional pills) or dosage.
One of the popular generics of Viagra is Nizagara, a drug based on the same active ingredient Sildenafil Citrate. Nizagara is available in one dosage option - 100 mg, which is the maximum allowable daily dose of the active substance. Produced by a young Indian pharmaceutical company, Globeasia Pharmaceuticals, this drug has only been on the market for about a year, but it has already earned a good reputation for its low price, high quality and fewer side effects compared to branded drugs. Thanks to such a medicine as Nizagara, many men are able to effectively get rid of problems with potency and fully enjoy a full-fledged sex life again, which was inaccessible to a wide range of the population due to the high prices for branded Viagra.
This medicine is indicated for men over 18 years of age with symptoms of erectile dysfunction, that is, those who are unable to achieve or maintain an erection of the penis sufficient for a successful sexual intercourse.
Nizagara pills are traditional round film-coated pills to be taken with water. They are produced in a round shape, in the middle there is a guide line, thanks to which you can easily and accurately divide the tablet into two parts, receiving 50 mg in one dose. This option is suitable for men with moderate or mild symptoms of erectile dysfunction. Before taking this medication, it is recommended that you first consult with your doctor to identify possible contraindications or restrictions on use. Nazagara is taken orally about an hour before planned sexual activity. In severe ED, the dose is increased to 100 mg, and for minor potency problems, mainly due to psychological reasons, a dosage of 25 mg can be used. It can be obtained by dividing the tablet into four parts, only this should be done very carefully using a special splitter. In this case, the maximum frequency of use of the drug, regardless of the dosage, is once a day. For elderly patients over the age of 65 years and with concomitant impaired renal or hepatic function, the recommended dose is 25 mg. There are 10 tablets in one blister, usually one or two blisters in a package.
Before you start taking Nizagara, like any other Viagra generics, you should undergo an examination of the cardiovascular system.
This medicine should be used with caution in men with anatomical deformity of the penis and in men with diseases that predispose to the development of priapism. Nizagara shouldn't be used in patients for whom sexual activity is undesirable. These include mainly conditions associated with decompensated severe cardiovascular diseases.
Nizagara should be prescribed with caution to patients with peptic ulcer of the stomach and duodenum in the acute phase, as well as in chronic gastritis. Special attention has to be paid to diseases of the retina, especially hereditary ones, for example, hereditary retinitis pigmentosa.
Like other Viagra generics from the low price category, Nizagara is a drug that cannot be found on the shelves of ordinary offline pharmacies in the United States. This is due to the strict protectionist pharmaceutical policy of the United States, which vehemently supports Pfizer, the US manufacturer of the branded Viagra. It is despite the fact that the patent protection for Viagra has expired several years ago, and today any pharmaceutical company has the right to use the finished dosage formula of Viagra and produce its own generic version of this drug.
The American pharmaceutical market has to accept the rules of the game imposed by Big Pharma. However, for people who cannot afford to spend big money on potency recovery pills, there is an easy and convenient way to get Nizagara 100 mg at a low price: make an order from an online pharmacy. So many online pharmacies based both directly in India and various international pharmacies, the so-called drug resellers, have this effective and safe medicine for erectile dysfunction in their assortment. All it takes to make a purchase is to make a search query like Nizagara 100mg buy online, and you will be presented with literally dozens of major pharmacies that ship the coveted drug in the US. The process of making a purchase is exactly the same as in any online store, payment is made by card on the site. For particularly law-abiding consumers who fear that it may be illegal to buy anti-ED drugs from abroad, we emphasize that there is not a single law that would prohibit such a purchase of both this drug and, in general, most modern drugs to improve potency. A nice bonus that will please men who don't like visits to the doctor: when buying generic Viagra online from India, you will not be required to present a prescription, because in this country the prescription status of Sildenafil citrate is purely advisory.
Buying Nizagara 100 mg, you save a significant amount of money and get the drug just as effective and safe as the branded one.
Sildenafil is rapidly absorbed after oral administration. The absolute bioavailability of this substance averages 40% and varies depending on the individual sensitivity of the male organism. After a single oral dose of 100 mg, the maximum concentration of Sildenafil is achieved when taken on an empty stomach for 30-120 minutes. When taking Nizagara in combination with fatty foods, the rate of absorption of Sildenafil decreases; the time before the start of absorption increases to 60 minutes, and its maximum concentration in the blood (and efficiency) decreases by an average of 30%. Nizagara remains in the system for up to 6 hours. It is not recommended to combine Nizagara with alcohol, fatty and abundant food, if you want the drug to be as efficient as possible.
The active ingredient of both Nizagara and Viagra is Sildenafil citrate.
Sildenafil is a strong and highly selective inhibitor of cGMP-specific phosphodiesterase type 5 (PDE-5), which is responsible for the breakdown of cGMP in the cavernous bodies of the penis. Sildenafil does not have a direct relaxing effect on the cavernous bodies, but actively enhances the relaxing effect of nitric oxide on this tissue. During sexual arousal, a radical release of NO occurs under the influence of sildenafil, which leads to inhibition of PDE5 and an increase in the level of cGMP in the cavernous bodies. As a result, the smooth muscles of the arteries relax and blood flow increases in the cavernous bodies of the penis, which leads to a strong and prolonged erection. In this case, the hormonal system of a man is not subjected to any stimulation, as well as the psycho-emotional one.
Therefore, according to the principle of action, indications and contraindications, Nizagara and Viagra do not differ at all from each other.
In terms of side effects, Nizagara has more benefits here. Brand Viagra is an effective drug that can cope with the symptoms of erectile dysfunction of almost any severity and etiology, but many users complain of severe side effects.
From the side of the central nervous system, they include headache, flushing of the skin of the face, dizziness, insomnia; from the side of the digestive system - dyspepsia, asthenia, diarrhea, abdominal pain, nausea. On the part of the musculoskeletal system, arthralgia, myalgia, increased muscle tone are observed. On the part of the respiratory system - nasal congestion, pharyngitis, rhinitis, respiratory failure. Many patients are afraid of side effects from the organs of vision: changes in color perception, especially of green and blue shades. Conjunctivitis may also develop.
Of course, all these side effects don't appear simultaneously in one person. However, taking Nizagara provokes the occurrence of a much smaller number of such unpleasant adverse reactions, they are less pronounced and disappear more quickly after the start of therapy. This is due to the enhanced purification of the main ingredient.
Medically reviewed by: Abraham Lincoln Woods III